Mynox® Mycoplasma Elimination Reagent

Mynox® jebiologický reagent ktorý sa selektívne integruje do membrány mykoplazmy, čo má za následok jej rozpad a následné zahubenie. Bez rezistencie a cytotoxického efektu. 1 aplikácia určená na „vyliečenie“ jednej bunkovej línie. Bez pridaných antibiotík, mykoplazma je zničená v priebehu 2-3 hodín.

5 ošetrení

The classic Mynox® is an antibiotic-free formulation; its activity is based on a biophysical mechanism, thus there is no development of resistant strains. Mycoplasma are permanently destroyed within 2-3 hours.

Benefits

Free of antibiotics

Recommended Use / Scope

Mynox® is intended for research use only. Not applicable for clinical treatment. The direct treatment of enveloped viruses is not possible.

Kit Components

Mynox® is a sterile, ready-to-use solution, aliquoted per tube for single use, 200 µl per vial.

Package Sizes

1 application can be used to cure one cell culture permanently from mycoplasma burden.

• Cat. No. 10-0200      2 applications
• Cat. No. 10-0500      5 applications
• Cat. No. 10-1000    10 applications

Result Evaluation

Elimination success should be verified with a suitable mycoplasma detection system, e.g. Minerva Biolabs’s Venor®GeM Mycoplasma PCR Detection Kits.

Required Consumables

6-well tissue culture plate or small tissue culture petri dish (6 mm Ø)
Regular cell culture plastics

Required Lab Devices

Regular cell culture equipment (incubator, centrifuge, pipettes, etc.)

Shelf Life and Storage

Kit components are maintainable at +2 to +8 °C for at least 6 months.

Fig. Electron micrograph showing the effects of Mynox® when applied to contaminated cell cultures. (A) Mycoplasma contaminated cell culture before treatment. (B) With one application of Mynox® membranes of all mycoplasma are destroyed while the tissue cell membrane is unaffected. Black arrows indicate mycoplasmas, white arrows indicate parts of a tissue cell.